Ayana Prewitt was born in Houston, Texas and has one sibling, Zaire Prewitt. At the age of 8 she decided that she wanted to pursue an acting career and was discovered by Page Parkes Talent where she was featured in commercials, print media, and fashion events. She was featured in theatrical roles in "The Wind and the Willows" (2012) and "Bugsy Malone" (2013) at the Katy Visual and Performing Arts Theatre. Most recently she is known as Katarina in the short film "Burn" (2016).
In 2013 Ayana started living in Los Angeles, CA after signing with AEFH Talent Agency. She has been featured in short films "Special Valentine" (2014), "Summer in the Water" (2014), Promo for Food Network (Venice Beach Food Truck Brawl-2014), and a PSA "Erin's Law Changing the World Campaign" (2015).